Steroids and derivatives
Sigma Aldrich Fine Chemicals Biosciences beta-Estradiol 17-beta-D-g10MG
BETA7 beta-Estradiol 17-beta-D-g10MG
Perkin Elmer US LLC Gateway Controller for ATR Trough Top Plate - ZnSe, UK
The controller has a temperature range from ambient to 200°C, in 1°C increments. This controller is compatible with the Spectrum 3/Frontier spectrometer.
Cayman Chemical GlycocholIc AcId 5g
A glycine-conjugated form of cholic acid; has roles in the emulsification of fats; reduces expression of the gene encoding FXR and increases expression of the genes encoding the bile acid receptors TGR5 and S1PR2 in SNU-245 cells at 1.6 μmol/ml; increases the intracellular accumulation and cytotoxicity of epirubicin in Caco-2 cells at 250 μM, as well as decreases expression of the genes encoding MDR1, MRP1, and MRP2 when used alone or in combination with epirubicin; increases absorption of epirubicin into everted sacs of rat ileum and jejunum at 250 μM; bile acid composition ratio of glycocholic acid is elevated in bile of patients with cholangiocarcinoma compared with patients with pancreatic cancer or benign biliary diseases; serum levels are elevated in patients with hepatocellular carcinoma compared with healthy individuals
Cayman Chemical GlycocholIc AcId 10g
A glycine-conjugated form of cholic acid; has roles in the emulsification of fats; reduces expression of the gene encoding FXR and increases expression of the genes encoding the bile acid receptors TGR5 and S1PR2 in SNU-245 cells at 1.6 μmol/ml; increases the intracellular accumulation and cytotoxicity of epirubicin in Caco-2 cells at 250 μM, as well as decreases expression of the genes encoding MDR1, MRP1, and MRP2 when used alone or in combination with epirubicin; increases absorption of epirubicin into everted sacs of rat ileum and jejunum at 250 μM; bile acid composition ratio of glycocholic acid is elevated in bile of patients with cholangiocarcinoma compared with patients with pancreatic cancer or benign biliary diseases; serum levels are elevated in patients with hepatocellular carcinoma compared with healthy individuals
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
Medchemexpress LLC D3/5-HT receptor modulator-1 | 898532-85-9 | 99.8% | 391.51 g·mol⁻¹ | C24H29N3O2 | 5 MG
D3/5-HT receptor modulator-1 (compound 5i) is a small-molecule research reagent with a mixed dopaminergic and serotonergic profile. It functions as a selective dopamine D3 receptor antagonist, a 5-HT2A receptor antagonist, and a partial 5-HT1A receptor agonist, and is intended for in vitro and preclinical studies investigating receptor pharmacology and antipsychotic-like mechanisms.
- Selective dopamine D3 receptor antagonist, 5-HT2A receptor antagonist, and partial 5-HT1A receptor agonist.
- High purity (≈99.8%).
- Molecular formula C24H29N3O2 and molecular weight 391.51 g·mol⁻¹.
- Suitable for in vitro and preclinical receptor pharmacology studies.
- Available in small milligram packages for assay screening.
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
Medchemexpress LLC Paramethasone acetate | 1597-82-6 | 98.0% | 434.50 g/mol | C24H31FO6 | 10 MG
Paramethasone acetate is a synthetic glucocorticoid acetate supplied as a solid research reagent with reported purity of 98% and a molecular weight of 434.50 g/mol. It is used in research to study anti-inflammatory and immunosuppressive effects, glucocorticoid receptor activity, and related signaling pathways. Storage recommendations and an SDS are provided for safe handling and stability considerations.
- High listed purity suitable for research applications.
- Supplied as a solid powder for precise dosing and solution preparation.
- Useful for in vitro and preclinical studies of glucocorticoid activity.
- Provides storage and stability guidance for powder and solutions.
- Accompanied by safety data and documentation for laboratory use.
Medchemexpress LLC Cagrilintide acetate | 1415456-99-3 | CB712152538 | 99.96% | 4409.01 | 5 MG
Cagrilintide acetate is a non-selective AMYR/CTR agonist and a long-acting acylated amylase analogue. It reduces food intake and causes significant weight loss in a dose-dependent manner, making it suitable for obesity studies.
- Non-selective AMYR/CTR agonist
- Long-acting acylated amylase analogue
- Reduces food intake
- Causes significant weight loss in a dose-dependent manner
- Suitable for obesity studies
- For research use only
Medchemexpress LLC Estradiol-d5 | 221093-45-4 | 99.1% | 1 MG
Estradiol-d5 is a deuterium-labeled form of Estradiol. Estradiol is a steroid sex hormone crucial for maintaining fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during the drug development process.
Medchemexpress LLC Medroxyprogesterone (Standard) | 520-85-4 | 99.3% | 25 MG
Medroxyprogesterone (Standard) is the analytical standard for Medroxyprogesterone, intended for research and analytical applications. It is a white to off-white solid with a molecular weight of 344.49 and a chemical formula of C₂₂H₃₂O₃. This product is commonly used in qualitative, quantitative, and methodological research experiments.
- Analytical standard for Medroxyprogesterone
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
- Appears as a white to off-white solid
- Molecular weight of 344.49
- Chemical formula C₂₂H₃₂O₃